News

Connect Yorkshire Investment Forum 7th July
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Yorkshire Concept Board Meeting June 2010
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Yorkshire Concept Board Meeting, March 2010
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Venturefest winners
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Case Studies

Human Monoclonal Antibodies against the αIIβ3 Integrin

There are significant limitations in the use of mouse-derived antibodies, primarily because they elicit an immune response that blocks their effectiveness. This would be reduced if completely abolished if you use human antibodies. Furthermore the major therapeutic antibody ReoPro, which inhibits thrombosis, has been shown to react with both αIIbβ3 and αVβ3 with equal affinity and has been shown to distribute between platelets and endothelial cells. This coupled with a variety other interactions including the effect of shear stress means there is a potential to develop a range of antibodies of increased effectiveness. Thus specific anti-αIIbβ3 human monoclonal Fabs should have improved therapeutic characteristics and the strategy outlined below will allow the development of antibodies with different binding characteristics and therefore different and enhanced therapeutic potential.

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Electronic Detection of Disease Biomarkers

The University of Leeds has developed breakthrough technology using semiconductor devices to detect microscopic traces of proteins, including biomarkers of specific diseases. This could move many medical diagnostic tests from the laboratory to the patient via a plug-in USB device that produces highly accurate results in minutes. For further details on eTect please click here. Proposal sponsored by the University of Leeds and approved at the October 2009 Yorkshire Fund Board meeting

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Welcome to Yorkshire Concept:

Proof of Commercial Concept Fund 2007-2010

Yorkshire Concept is a new project Fund designed to stimulate the commercialisation of research and knowledge-based activities in the Higher Education Institutions (HEIs) across the Yorkshire and the Humber region. It is funded jointly, on the principle of matched funding, by the Regional Development Agency, Yorkshire Forward, and the Higher Education Institutions themselves.

Activities will focus on supporting projects which enhance potential for a new product or process to become commercially viable and on forging collaborations between higher education and private sectors to encourage innovation.

Our Partners

Central to the success of the Yorkshire Concept : Proof of Commercial Fund are the partnerships between the Fund, the Higher Education Institutions (HEIs) in the region and Yorkshire Forward, the Regional Development Agency.

Allocated funding is matched 50% from the Fund sourced by Yorkshire Forward and 50% from the HEIs with £3 million being contributed from each source over a 3 year period, creating a £6m Fund. In addition we work closely with the Yorkshire Enterprise Fellowship scheme

Our partners are listed below:

Venturefest 2010

The Fund helped sponsor Venturefest Yorkshire 2010 using the opportunity to showcase around 30 propositions in the university showcase staff area, demonstrating the commercial potential of a wide range of science, technology and knowledge propositions from the regions higher education and research sector. In addition mr shox a spin out from the University of Sheffield won the event's Investment Competition. Find out more about Venturefest 2010.

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